What Is PDRN? The Renewal Ingredient Behind VOUX™ Red Ampoule
If you've spent time exploring Korean skincare, you may have come across PDRN, one of the category's most closely watched renewal ingredients. Once discussed primarily in professional aesthetic settings, PDRN is now gaining attention in topical skincare formulations such as VOUX Red Ampoule.
PDRN, in One Line
Derived from purified DNA fragments, used at cosmetic concentrations in VOUX™ Red Ampoule to help support a more revitalized, repaired-looking complexion overnight.
Find Your VOUX AmpouleWhat Is PDRN?
PDRN stands for polydeoxyribonucleotide, an ingredient derived from purified DNA fragments, listed on labels as Sodium DNA. Used at cosmetic concentrations in VOUX™ Red Ampoule, PDRN supports the skin's look and feel without replicating any in-office or medical procedure.
PDRN stands for polydeoxyribonucleotide, an ingredient derived from purified DNA fragments (on cosmetic ingredient labels, it typically appears as Sodium DNA). PDRN has been studied in professional and clinical settings, contributing to growing interest in its use in topical skincare. In skincare formulations like VOUX Red, it's used at cosmetic concentrations to help support the skin's look and feel; it is not a substitute for, and does not replicate, any in-office procedure.
Why Formulators Use It
Formulators use PDRN to help support skin's natural-looking resilience, hydration, and renewal over time. It has become a notable ingredient in premium Korean ampoules, including VOUX™ Red Ampoule, formulated to address visible signs of aging like fine lines and loss of firmness.
PDRN is valued for helping support the skin's natural-looking resilience, hydration, and renewal over time. It has become a notable ingredient in premium Korean ampoules formulated to address visible signs of aging, including fine lines and loss of firmness.
What Emerging Research Says About Topical PDRN
A 2026 randomized, double-blind study on a 0.1% PDRN-850K eye cream found improvements in periocular wrinkle appearance and measured skin-density and firmness over 28 days. That study covers its own specific formulation only, not VOUX Red, but reflects PDRN's growing research base.
Research into topical PDRN continues to develop. In a 2026 randomized, double-blind study, a specific 0.1% PDRN-850K eye cream was associated with improvements in the appearance of periocular wrinkles and measured skin-density and firmness parameters over 28 days, with good tolerability. These findings apply to the specific formulation studied and are not clinical testing of VOUX Red. Still, this emerging research helps explain why PDRN has become one of Korean skincare's most closely watched renewal ingredients.
What's Actually in VOUX Red
VOUX™ Red Ampoule is formulated with PDRN alongside a multi-peptide complex, Niacinamide, Adenosine, Centella Asiatica, and multi-molecular Hyaluronic Acid. Together, these ingredients support hydrated, smoother-, firmer-, and more youthful-looking skin as part of a concentrated nighttime renewal ritual.
PDRN may be Red's hero ingredient, but the complete formula is the VOUX difference. Red is formulated with 1.00% PDRN alongside a multi-peptide complex, niacinamide, adenosine, centella and multi-molecular hyaluronic acid. Together, these ingredients help support hydrated, smoother-, firmer- and more youthful-looking skin as part of a concentrated nighttime ritual. Want the full ingredient breakdown for Red? See The Renewal Science Behind VOUX Red Ampoule.
Who Red is best for: Red is best suited for skin showing visible signs of aging, fatigue, or loss of firmness. It's most commonly used in the evening to support overnight renewal. One note: because Red is a concentrated renewal-focused formula, we don't recommend layering it on the same night as a retinoid or tretinoin. Read more in our FAQ.
Shop Red
PDRN may be the ingredient that brings you to Red, but the complete formula is what makes it part of a thoughtful nighttime ritual.
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Explore the 3-in-1 SystemThis content is for educational purposes and reflects how certain ingredients are used in skincare formulation generally. VOUX Skincare products are cosmetics, not drugs, and are not intended to diagnose, treat, cure, or prevent any disease or medical condition, or to replicate the effects of in-office or medical procedures.
VOUX™ Trilight Complex® - Red Ampoule - Rejuvenation + Renewal
$85.00